Shop our selection of Weed Killer in the Outdoors Department at The Home Depot..Shop gr weed killer in the weed control section of Lowes.com. Find quality gr weed killer online or in store..Shop our selection of Weed GrKiller in the Outdoors Department at The Home Depot..It can kill root and all in one spraying. Like the vinegar weed killer, it is non selective. Yes, this is a chemical spray. I mention it because some of you may find it acceptable. There is strong commentary by both advocates and critics regarding the safety of this product. Glyphosate is the active ingre.nt and may not be as bad as some other chemicals, in terms of lingering in the soil .